V
Viral Blast Daily

Can HBsAg be positive after vaccination?

Author

Rachel Ellis

Published Apr 14, 2026

Can HBsAg be positive after vaccination?

Published studies have found that transient HBsAg-positivity can be detected for up to 18 days after HepB vaccination (up to 52 days among hemodialysis patients).

What is the minimum protective titer of anti-HBs?

For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. Any value between 5 and 12 mIU is indeterminate and should be repeated.

What happens if Hep B titer is negative?

If all of your hepatitis tests are negative, it indicates that you have not been exposed to the virus (or received the shot) and are not immune. If this is the case, talk to your healthcare provider about getting immunized, whether or not you have risk factors for acquiring hepatitis B.

What is anti-HBs blood test?

anti-HBs or HBsAb (Hepatitis B surface antibody) – A “positive” or “reactive” anti-HBs (or HBsAb) test result indicates that a person is protected against the hepatitis B virus. This protection can be the result of receiving the hepatitis B vaccine or successfully recovering from a past hepatitis B infection.

Can you still get hepatitis B after vaccination?

The good news is that hepatitis B is vaccine preventable. This means that after you complete the vaccine series, you cannot contract hepatitis B through any modes of transmission; you are protected for life!

How long is a titer good for?

How often should titers be checked? A three-year interval is appropriate for the majority of adult dogs and cats when quantitative tests are used. The manufacturers of in-clinic (“yes/no”) screening tests recommend they be used annually.

What is anti-HBs non reactive?

Normal results are negative or nonreactive, meaning that no hepatitis B surface antigen was found. If your test is positive or reactive, it may mean you are actively infected with HBV. In most cases this means that you will recover within 6 months.

When does anti-HBs appear?

HBsAg will be detected in an infected person’s blood an average of 4 weeks (range: 1–9 weeks) after exposure to the virus.

What is the dosing for hepatitis B vaccine?

Recommended Doses of Hepatitis B Vaccine

VaccineAge GroupDosage
Engerix-B (GlaxoSmithKline)20 years & older3 doses
Recombivax HB (Merck)0-19 years3 doses
11-15 years2 doses
20 years & older3 doses

How long does immunity last from hepatitis B vaccine?

How long does protection from hepatitis B vaccine last? Studies indicate that immunologic memory remains intact for at least 30 years among healthy people who initiated hepatitis B vaccination at >6 months of age (16).